Bricanyl

Terbutaline
Systematic (IUPAC) name
5-(1-hydroxy-2-tert-butylamino-ethyl)benzene-1,3-diol
Identifiers
CAS number	23031-25-6
ATC code	R03AC03 R03CC03
PubChem	5403
DrugBank	APRD00589
Chemical data
Formula	C12H19NO3
Mol. weight	225.284 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	gut wall, liver
Half life	5.5-5.9 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	B
Legal status
Routes	oral, SQ, inhaled

The drug Terbutaline (trade names Brethine, Bricanyl, or Brethaire) is a β₂-adrenergic receptor agonist, used as a fast-acting bronchodilator (often used as a short-term asthma treatment) and as a tocolytic to delay premature labour. The inhaled form of terbutaline starts working within 15 minutes and can last up to 6 hours.

Terbutaline as a treatment for premature labour is an off-label use not approved by the FDA. Recent studies have suggested that terbutaline is a developmental neurotoxicant and may cause brain damage to the infant. (J Pharmacol Exp Ther. 2004 Feb;308(2):529-37. Epub 2003 Nov 10.)